E-ISSN 1658-8088 | ISSN 1658-807X
 

Original Article

Online Publishing Date:
01 / 01 / 2019

 


Agreement within couples on choosing preimplantation genetic diagnosis versus pre-natal diagnosis: perspective from Saudi population.

Fawz AlHarthi , Moeen Al Sayed, Ahmed Yaqinuddin, Gulsan Abubakar Karbani, Ameera Salem Blobaid, Monika Maya Wahi .


Abstract
Background: Couples who are at risk for having an infant with a serious genetic disorder can benefit from pre-implantation genetic diagnosis (PGD), but many couples still opt for the riskier pre-natal diagnosis (PND). Although couples make this decision together, the male and the female in the couple may have different attitudes toward choosing PGD vs. PND. The objective of this study was to determine if men and women in the same couple with at least one child with a genetic disorder will have significantly different attitudes toward choosing PGD vs. PND.
Methodology: In this cross-sectional clinical study, couples with at least one child with a genetic disease attending the King Faisal Specialist Hospital Research Center, Genetic Counseling Clinic (KFSH-RC, GCC), Riyadh, Saudi Arabia were asked to complete an anonymous survey about their attitudes towards PGD vs. PND. The responses were compared between men and women in couples. The study was conducted during May 2017.
Results: A total of 38 couples provided complete surveys. In terms of preference for PGD vs. PND, there were no significant differences in aggregate between men and women (p > 0.05). Over half the couples agreed (were concordant) on all statements about PGD vs. PND. An almost equal number of couples with members who disagreed (were discordant) had women preferring PND vs. men preferring PND compared to PGD.
Conclusion: This study showed that members of couples sampled were generally in agreement about their preference for PGD vs. PND. Among discordant couples, there was no preference among women for PGD vs. PND. Studies like this are important to help clinicians understand intra-couple dynamics in genetic counseling.

Key words: Genetic Counseling, preimplantation diagnosis, prenatal diagnosis, consanguinity, health knowledge, attitudes, practice


 
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How to Cite this Article
Pubmed Style

FA, Sayed MA, Yaqinuddin A, Karbani GA, Blobaid AS, MMW, . Agreement within couples on choosing preimplantation genetic diagnosis versus pre-natal diagnosis: perspective from Saudi population.. JBCGenetics. 2019; 2(1): 18-27. doi:10.24911/JBCGenetics/183-1538333316


Web Style

FA, Sayed MA, Yaqinuddin A, Karbani GA, Blobaid AS, MMW, . Agreement within couples on choosing preimplantation genetic diagnosis versus pre-natal diagnosis: perspective from Saudi population.. https://www.jbcgenetics.com/?mno=10650 [Access: March 13, 2024]. doi:10.24911/JBCGenetics/183-1538333316


AMA (American Medical Association) Style

FA, Sayed MA, Yaqinuddin A, Karbani GA, Blobaid AS, MMW, . Agreement within couples on choosing preimplantation genetic diagnosis versus pre-natal diagnosis: perspective from Saudi population.. JBCGenetics. 2019; 2(1): 18-27. doi:10.24911/JBCGenetics/183-1538333316



Vancouver/ICMJE Style

FA, Sayed MA, Yaqinuddin A, Karbani GA, Blobaid AS, MMW, . Agreement within couples on choosing preimplantation genetic diagnosis versus pre-natal diagnosis: perspective from Saudi population.. JBCGenetics. (2019), [cited March 13, 2024]; 2(1): 18-27. doi:10.24911/JBCGenetics/183-1538333316



Harvard Style

, F. A. ., Sayed, M. A., Yaqinuddin, A., Karbani, G. A., Blobaid, A. S., , M. M. W. . & (2019) Agreement within couples on choosing preimplantation genetic diagnosis versus pre-natal diagnosis: perspective from Saudi population.. JBCGenetics, 2 (1), 18-27. doi:10.24911/JBCGenetics/183-1538333316



Turabian Style

, Fawz AlHarthi , Moeen Al Sayed, Ahmed Yaqinuddin, Gulsan Abubakar Karbani, Ameera Salem Blobaid, Monika Maya Wahi, and . 2019. Agreement within couples on choosing preimplantation genetic diagnosis versus pre-natal diagnosis: perspective from Saudi population.. Journal of Biochemical and Clinical Genetics, 2 (1), 18-27. doi:10.24911/JBCGenetics/183-1538333316



Chicago Style

, Fawz AlHarthi , Moeen Al Sayed, Ahmed Yaqinuddin, Gulsan Abubakar Karbani, Ameera Salem Blobaid, Monika Maya Wahi, and . "Agreement within couples on choosing preimplantation genetic diagnosis versus pre-natal diagnosis: perspective from Saudi population.." Journal of Biochemical and Clinical Genetics 2 (2019), 18-27. doi:10.24911/JBCGenetics/183-1538333316



MLA (The Modern Language Association) Style

, Fawz AlHarthi , Moeen Al Sayed, Ahmed Yaqinuddin, Gulsan Abubakar Karbani, Ameera Salem Blobaid, Monika Maya Wahi, and . "Agreement within couples on choosing preimplantation genetic diagnosis versus pre-natal diagnosis: perspective from Saudi population.." Journal of Biochemical and Clinical Genetics 2.1 (2019), 18-27. Print. doi:10.24911/JBCGenetics/183-1538333316



APA (American Psychological Association) Style

, F. A. ., Sayed, M. A., Yaqinuddin, A., Karbani, G. A., Blobaid, A. S., , M. M. W. . & (2019) Agreement within couples on choosing preimplantation genetic diagnosis versus pre-natal diagnosis: perspective from Saudi population.. Journal of Biochemical and Clinical Genetics, 2 (1), 18-27. doi:10.24911/JBCGenetics/183-1538333316





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