Prevention of hemoglobinopathies in Saudi Arabia: efficacy of national premarital screening and the feasibility of preimplantation genetic diagnosis

Muhammad Umair; Majid Alfadhel

doi:10.24911/JBCGenetics/183-1595487640

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Online Published: 19 Sep 2020

JBCGenetics. 2020; 3(2): 94-99

doi: 10.24911/JBCGenetics/183-1595487640

Prevention of hemoglobinopathies in Saudi Arabia: efficacy of national premarital screening and the feasibility of preimplantation genetic diagnosis

Muhammad Umair, Majid Alfadhel.

Abstract
Hemoglobinopathies constitute the most frequent, inherited single-gene disorders. Its prevalence is increasing substantially and might cause a substantial economic burden on affected families and countries. The current study findings recommend population screening strategies to be implemented for severe disorders such as sickle-cell disease, hemoglobin E disease, α- and β-thalassemia, and normal individuals to identify the carrier status and manage the disease pathogenesis. In addition, national registries should highlight the information and contribute to the proper management and care of patients suffering from hemoglobinopathy. Furthermore, the Saudi Government should provide a conceptual framework to determine the specific preventive strategies to manage the incidence of hemoglobinopathies effectively.

Key words: Hemoglobinopathies, sickle cell, α-thalassemia, newborn population screening, β-thalassemia

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Pubmed Style

Umair M, Alfadhel M. Prevention of hemoglobinopathies in Saudi Arabia: efficacy of national premarital screening and the feasibility of preimplantation genetic diagnosis. JBCGenetics. 2020; 3(2): 94-99. doi:10.24911/JBCGenetics/183-1595487640

Web Style

Umair M, Alfadhel M. Prevention of hemoglobinopathies in Saudi Arabia: efficacy of national premarital screening and the feasibility of preimplantation genetic diagnosis. https://www.jbcgenetics.com/?mno=108572 [Access: November 14, 2024]. doi:10.24911/JBCGenetics/183-1595487640

AMA (American Medical Association) Style

Umair M, Alfadhel M. Prevention of hemoglobinopathies in Saudi Arabia: efficacy of national premarital screening and the feasibility of preimplantation genetic diagnosis. JBCGenetics. 2020; 3(2): 94-99. doi:10.24911/JBCGenetics/183-1595487640

Vancouver/ICMJE Style

Umair M, Alfadhel M. Prevention of hemoglobinopathies in Saudi Arabia: efficacy of national premarital screening and the feasibility of preimplantation genetic diagnosis. JBCGenetics. (2020), [cited November 14, 2024]; 3(2): 94-99. doi:10.24911/JBCGenetics/183-1595487640

Harvard Style

Umair, M. & Alfadhel, . M. (2020) Prevention of hemoglobinopathies in Saudi Arabia: efficacy of national premarital screening and the feasibility of preimplantation genetic diagnosis. JBCGenetics, 3 (2), 94-99. doi:10.24911/JBCGenetics/183-1595487640

Turabian Style

Umair, Muhammad, and Majid Alfadhel. 2020. Prevention of hemoglobinopathies in Saudi Arabia: efficacy of national premarital screening and the feasibility of preimplantation genetic diagnosis. Journal of Biochemical and Clinical Genetics, 3 (2), 94-99. doi:10.24911/JBCGenetics/183-1595487640

Chicago Style

Umair, Muhammad, and Majid Alfadhel. "Prevention of hemoglobinopathies in Saudi Arabia: efficacy of national premarital screening and the feasibility of preimplantation genetic diagnosis." Journal of Biochemical and Clinical Genetics 3 (2020), 94-99. doi:10.24911/JBCGenetics/183-1595487640

MLA (The Modern Language Association) Style

Umair, Muhammad, and Majid Alfadhel. "Prevention of hemoglobinopathies in Saudi Arabia: efficacy of national premarital screening and the feasibility of preimplantation genetic diagnosis." Journal of Biochemical and Clinical Genetics 3.2 (2020), 94-99. Print. doi:10.24911/JBCGenetics/183-1595487640

APA (American Psychological Association) Style

Umair, M. & Alfadhel, . M. (2020) Prevention of hemoglobinopathies in Saudi Arabia: efficacy of national premarital screening and the feasibility of preimplantation genetic diagnosis. Journal of Biochemical and Clinical Genetics, 3 (2), 94-99. doi:10.24911/JBCGenetics/183-1595487640

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